In the 1940s, Prince Mohamed Ali Ibrahim built a new palace for himself and his family at Number 40, Road 78, in Maadi. The actual occupants of the house were Princess Hanezada, her husband, and their children. After the 1952 Revolution, this palace, modest by royal standards, was taken over by the government, and in 1955 it was rented to Cairo American School. The villa on Road 7 was seriously overcrowded with 162 students in its last year.
The first alteration was to change the institution's name from Cairo American School to Cairo American College in 1955, in an apparent attempt to enhance its status. At the elementary and junior high school levels, curricular emphasis was on reading, writing, and arithmetic, with supplemental courses in science, social science, music, art and physical education. High school courses varied somewhat from year to year according to the needs of the students. Still, the standard program included four years of English, French, mathematics, science, and social studies, with electives in Latin, art, music, journalism, drama, typing, and Arabic. French was taught at all levels, from the first grade through the senior year in high school. In general, the curriculum was designed to be typical of a good American school at the time. It also offered courses in French and Arabic, and emphasized the history and geography of the Middle East and Asia. The program was intended to prepare students for higher education and most of the graduates of CAC did go on to college or university.